A Scientific Review of Personalized Vitamins

2 min read

You're a unique creature. We're all different, including our nutritional intakes, our metabolisms, our exposures and our genetics.

But these differences are nuanced, and they're not just skin-deep—they're cell deep. That's why toggling through an online vitamin quiz in the hopes of "better skin" or "stronger bones" merely scratches the surface, as well-intentioned as it might be. Done right, finding personalized supplements should include comprehensive testing that can help identify any unexpected nutritional needs a person might have. And it should probably be done with the help of a doctor.*

Custom Vitamins and the Science Behind Them

The dream would be to look at a battery of all kinds of tests, but that’s a ways away from being the current norm. Why? Because it can be costly, difficult to collect and needs to be analyzed in multiple labs. Currently, it’s possible to get an idea of what might help from a questionnaire or diet survey and even a few simple blood or urine tests. The key to making any findings worthwhile, however, is to work with a good physician or healthcare expert, or with a company that can support its recommendations with credible studies and data.

Personalized Vitamins May Just Complicate Things Even More

Let’s put it this way: how cluttered is your current supplement routine? One thing to look out for is ending up with a lot of different bottles of supplements. This can pretty easily lead you to take more than needed, when in reality, overdoing it on one nutrient can hinder the impact of another. When it comes to vitamins, less is more. Plus, it can get expensive.*

Our POV on Customized Supplements

Where do Ritual multivitamins fall on the spectrum and why did we choose to build it that way? The fact is that in the realm of nutritional needs, our bodies are often more alike than they are different. So our approach is to scour thousands of peer-reviewed, published scientific population data to pinpoint some of the gaps we share in our diet, with considerations like genetic variations, dietary restrictions, and lifestage.

Want an example? Up to one-third of the population has a genetic variation that makes it difficult to efficiently utilize folic acid, the synthetic form of folate—which is why we include methylated folate (a bioavailable version) in all our multivitamins. But pregnant women require more folate than women who aren't expecting, or postmenopausal women, or men, so we adjusted the amount accordingly in our Essential Prenatal. On the flip side, it's easier for women to get enough zinc from their diets than men—so we skipped zinc in our women's multivitamins and included it in Essential for Men. That's the type of personalization we can get behind.*

Meet Our Experts

This article features advice from members of our Scientific Advisory Board.

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Dr. Nima Alamdari

Chief Scientific Officer
Dr. Nima Alamdari is a Harvard-trained muscle physiologist specializing in health and sports science. With over 20 years of research involvement focused on muscle metabolism and physiology at some of the world's top-tier universities, he is dedicated to advancing cutting-edge science for optimal performance, fitness, and health. He previously served as a faculty member at Harvard Medical School and is currently a Chief Scientific Officer in industry, as well as an Honorary Professor at the University of Exeter, where he publishes influential research in sports science, nutrition, and medicine. A passionate athlete, he has completed all six of the world’s major marathons, including Boston, Chicago, New York, Tokyo, London, and Berlin. He lives (and runs) in Los Angeles.
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Dr. Luke Bucci, PhD, CCN, CNS

Research and Technical Fellow
Dr. Luke Bucci received a PhD in Biomedical Sciences from the University of Texas and has over thirty years of experience in the nutrition industry, encompassing all aspects of scientific applications. He has brought blockbuster products to market, written books, patents and numerous articles, and developed certification programs for clinical nutritionists.
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Dr. Mastaneh Sharafi

SVP, Scientific & Clinical Affairs
Dr. Mastaneh Sharafi is the Senior Vice President of Science and Innovation at Ritual, where she leads the translation of cutting-edge nutritional research into transformative, evidence-based nutrition solutions. A Ph.D. in Nutritional Sciences and a Registered Dietitian, Dr. Sharafi trained at Penn State University and the University of Connecticut and has authored dozens of scientific publications. With expertise spanning clinical studies, dietary patterns, chemosensory perception, and product innovation, she bridges rigorous science with real-world impact and is recognized for her influence within the broader healthcare and nutrition community. Passionate about making complex research accessible and actionable, Dr. Sharafi is committed to advancing public health through evidence-based innovation and a deeper understanding of the science behind what we eat.

Meet The Author

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Victoria Hoff

Writer
Victoria Hoff is an accomplished writer, journalist, and former wellness editor who has covered a wide variety of health, nutrition, and wellness topics during her tenure. She graduated Magna Cum Laude with a Bachelor of Arts from New York University, and after writing for Vogue, Elle, Byrdie, The/Thirty, and more, channeled her editorial skills into a marketing career.

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