Nutrition

Meet Synbiotic+, Our Game-Changing Gut Health Supplement*

4 min read

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We conducted two in-vitro studies on Synbiotic+—and the results were thrilling (to say the least).

Let’s check in: How’s your gut health game really going?

When it comes to matters of health, you deserve to be privy to the whole picture—which is that science indicates there’s much, much more to supporting gut microbiome balance than we initially thought. In other words, popping a probiotic supplement, or indulging in kimchi (or kombucha!) on the regular doesn’t necessarily mean bacterial benefits are being reaped.*

That’s why we created Synbiotic+—our daily 3-in-1 prebiotics, probiotics, and postbiotic supplement designed to help support gut, digestive, and immune health—specifically with survivability in mind. Sure, it took time—rigorous research, quality control testing, and in-vitro studies tend to do that—but in the end, we know the best things are worth the wait. Here’s what makes Synbiotic+ so innovative (and what helps set it apart).*

3-in-1 formula with traceable biotics

When it comes to multivitamins, we’re all about a “less is more” approach—that is, aiming to meet the majority of nutrient needs through a balanced diet, then supplementing to help fill the gaps. But when it comes to gut support, it turns out the landscape looks a little different: Whereas many nutrient needs can often be met via food alone, maintaining a balanced microbiome may not always be quite as simple as eating sauerkraut or yogurt.*

Put another way, while fermented foods—aka foods and beverages that are produced by controlled microbial growth—are associated with healthy diets (and some may even be associated with health benefits!), the live cultures naturally present are not the same as probiotics. That’s not to mention that many fermented foods and drinks, such as beer, wine, sourdough bread, and most commercial pickles, no longer include active cultures at the time of consumption—and that the cultures naturally present in fermented foods may not even be able to reach and colonize the large intestine, which is where a lot of the good stuff happens.* (1,2)

That’s why Synbiotic+ is special: Not only does it contain two of the world’s most clinically-studied probiotic strains (more on that soon), but the formula is Made Traceable™—that is, you can trace the supplier of each labeled ingredient and location of the final place of manufacturing. What’s more? It’s a 3-in-1 formula featuring probiotics, prebiotics, and a postbiotic (butyrate, to be specific)—which means all you have to worry about is taking your daily capsule.*

Essential reading → Prebiotics vs. Probiotics: What’s the Difference?

Science-backed, clinically-studied strains

Remember those clinically-studied strains we were talking about earlier? Let’s take a closer look at how they play into our formula. Synbiotic+ features two highly-documented probiotic strains, LGG® and BB-12®, as well as prebiotic bacteriophage PreforPro®—all of which are present in clinically studied doses. Translation: Synbiotic+ contains doses that are consistent with human clinical data, which may help alleviate the burden of wondering if the probiotic is effective.*

A note on CFUs and strains: Does quantity matter? Probiotics are typically measured in colony forming units (CFU). Colony forming units represent the number of probiotic cells in a sample that are capable of dividing and forming colonies—so if we’re trying to support the gut, the higher the better… right? Similarly, wouldn’t having a wide variety of strains be better than just a few? (2)

Actually, when it comes to probiotics, it’s less about the quantity of CFUs and strains and more about the quality of the evidence. According to the National Institutes of Health, “Higher CFU counts do not necessarily improve the product’s health effects.” Put another way, the effects of probiotics are not always contingent upon a higher CFU count—there’s more to the picture. Likewise, having more strains doesn’t mean the formula is better (in these cases, what should matter is the clinical testing behind the strains—are they supported by human clinical data?).* (2,3)

One pill a day—no refrigeration needed

Storing your gut health supplements in the fridge may not be the most convenient. Whether you travel, or just forget to look behind the juice, such limitations can stand in the way of committing to your daily habit. That’s why Synbiotic+ is so exciting. Not only is it shelf-stable (no fridge, no problem!), but it also provides gut support in just one mint-essenced pill a day. (Other brands can require constant refrigeration, so do a little research before committing.)*

When it comes to the delivery method, in order to prioritize preservation, our Scientific Team opted for a single-nested, delayed-release capsule to help reach the colon—an ideal place for probiotics to grow and thrive.*

Supported by in vitro testing

We also conducted two in vitro studies on Synbiotic+, the results of which were thrilling. While we recommend reading the article for a deeper dive into the study design and results, we’ll say this: In a model of the human GI tract, the majority of the prebiotic and probiotic blend survived transit through the stomach and small intestine, to be delivered to the colon. That’s not to mention that in our study modeling the human colon, Synbiotic+ was shown to significantly increase the growth of beneficial bacteria, microbial diversity, and the production of the short-chain fatty acid butyrate. Chef’s kiss.*

Next up → Shopping for a Probiotic? Look for These 4 Things

References:

  1. Dimidi, E., Cox, S.R., Rossi, M., & Whelan, K. (2019). Fermented foods: Definitions and characteristics, impact on the gut microbiota and effects on gastrointestinal health…. Nutrients, 11(8), 1806.
  2. Office of Dietary Supplements. Probiotics: Fact Sheet for Health Professionals. National Institutes of Health, Department of Health & Human Services. 2020.
  3. Guarner F, Sanders ME, Eliakim R, et al. World Gastroenterology Organization. World Gastroenterology Organisation Global Guidelines: Probiotics and Prebiotics. 2017.

Meet Our Experts

This article features advice and has been reviewed by members of our Science Team.

Science Thumb — Arianne

Arianne Vance, MPH, Research Scientist

Arianne Vance is a Senior Scientist at Ritual. She earned her MPH in Epidemiology from UCLA. Her graduate research focused on maternal and child health, with an emphasis on breastfeeding and maternal mental health. She is passionate about sharing her love of science by presenting cutting-edge research in an accessible and engaging way.

Science Thumb — Arianne

Arianne Vance, MPH, Research Scientist

Arianne Vance is a Senior Scientist at Ritual. She earned her MPH in Epidemiology from UCLA. Her graduate research focused on maternal and child health, with an emphasis on breastfeeding and maternal mental health. She is passionate about sharing her love of science by presenting cutting-edge research in an accessible and engaging way.

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