The only leading prenatal backed by a human clinical trial.‡†
When compared with another leading prenatal in a clinical trial over 24 weeks, Essential Prenatal was clinically proven to...
Support adequate folate levels. Essential Prenatal demonstrated a more efficient utilization of folate vs. a leading prenatal with folic acid and was clinically proven to be well-absorbed.†*
Support cortisol levels. Moms taking Essential Prenatal had a lower overall serum cortisol level during pregnancy than those taking a leading prenatal.†*
Help support baby’s bone health, as seen through higher umbilical cord blood P1NP levels, a measure of bone formation.†*
Be gentler on the stomach. Moms taking Ritual reported our prenatal to be easier to swallow, gentler on the stomach and a better overall positive experience than those taking a leading prenatal.†
LOWER OVERALL SERUM CORTISOL
HIGHER FETAL BONE HEALTH BIOMARKER
Moms taking Essential Prenatal had higher umbilical cord blood P1NP levels. P1NP is procollagen type 1 N-terminal propeptide, and acts as a measure of bone formation.3
About our Clinical Trial
Ritual is setting a new standard, with a groundbreaking 24-week clinical trial, employing a randomized, double-blind, controlled design. A total of 62 second and third trimester women, ranging from 21 to 45 years of age completed the study. The sample was racially and ethnically diverse, containing a range of educational backgrounds and marital statuses.
‡Based on net sales from industry data including Nielsen IQ, Stackline, and Numerator as of Q4, 2024 and top 5 products.
†Based on a 24-week, randomized, double-blind, controlled clinical trial on 62 second and third trimester pregnant women.
1 Shriyan P, Sudhir P, van Schayck OCP, Babu GR. Association of high cortisol levels in pregnancy and altered fetal growth. Results from the MAASTHI, a prospective cohort study, Bengaluru. Lancet Reg Health Southeast Asia. 2023 Jul;14:100196. doi: 10.1016/j.lansea.2023.100196. Erratum in: Lancet Reg Health Southeast Asia. 2024 Feb 21;24:100374. doi: 10.1016/j.lansea.2024.100374. PMID: 37461746; PMCID: PMC7614758.
2 AHA website 2021. Accessed 2025: https://www.heart.org/en/news/2021/05/06/prenatal-stress-can-program-a-childs-brain-for-later-health-issues
3 Szulc P. Bone turnover: Biology and assessment tools. Best Pract Res Clin Endocrinol Metab. 2018 Oct;32(5):725-738. doi: 10.1016/j.beem.2018.05.003. Epub 2018 May 26. PMID: 30449551.